Cisplatin pulmonary fibrosis

Author: oiwv

August undefined, 2024

WebMar 6, 2024 · Pulmonary fibrosis is a lung disease that occurs when lung tissue becomes damaged and scarred. This thickened, stiff tissue makes it more difficult for your lungs to work properly. As pulmonary fibrosis … WebPubMed Central (PMC)

Drug-Induced Pulmonary Fibrosis Pulmonary Fibrosis …

WebFeb 2, 2024 · Cisplatin, a potent chemotherapeutic agent used for treating various types of solid organ tumors, is limited by its serious side effects in clinical application ... Protective Effects of GHK-Cu in Bleomycin-Induced Pulmonary Fibrosis via Anti-oxidative Stress and Anti-inflammation Pathways. rcv with pod

PubMed Central (PMC)

WebThe clinical and histopathological data as well as the lack of an infectious cause indicate that pulmonary fibrosis was induced by oxaliplatin and 5-FU/folinic acid. Conclusion: This case demonstrates that treatment with oxaliplatin and 5-FU/folinic acid can cause acute pulmonary fibrosis. WebThe anticancer drug cisplatin induces cell death by apoptosis. Apoptosis is dependent on cellular loss of potassium ions (K+). We have recently shown that the antifungal drug amphotericin B (enhancin WebFeb 22, 2016 · In patients treated for disseminated testicular cancer with bleomycin, etoposide, and cisplatin (BEP), the risk of acute bleomycin-induced changes is ≤ 6.8%, with a 0% to 1% risk of death. 1 - 4 Serious long-term toxicity has been indicated with an increased risk of late mortality caused by pulmonary diseases. 5 These findings were … rcvda awards

Development of a best-practice clinical guideline for the use of ...

Effects of acute in vivo cisplatin and selenium treatment on ...

WebJan 1, 2011 · Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis. Cancer Res 2003;63(16):5054–5059. Medline, Google Scholar; 24 Wagner SA, … WebBackground: Gemcitabine is the only approved cytotoxic agent for the treatment of pancreatic cancer by the Food and Drug Administration. In addition, gemcitabine is also commonly used for the management of breast, ovarian, and non-small cell lung cancer. Myelosuppression is the most common toxicity of gemcitabine therapy. how to spear fish on landWebAug 7, 2024 · Its potent anti-inflammatory and anti-fibrotic effects were demonstrated in animal models of lung fibrosis including bleomycin-induced lung injury and fibrosis. Oku et al. showed that both prophylactic and therapeutic administration of pirfenidone attenuated lung fibrosis induced by intravenous bleomycin in mice [ 5 ]. rcv vichy foot

"WebPulmonary toxicity of cytotoxic agents Platinum compounds The administration of cisplatin and carboplatin, the 2 most commonly used platinum derivative agents, can lead to … " - Cisplatin pulmonary fibrosis

Cisplatin pulmonary fibrosis

Germ cell cancer in pregnancy- successfully treated with …

WebMar 12, 2024 · Interstitial inflammation, fibrosis, structural pulmonary damage, and other severe complications have also been reported during cisplatin chemotherapy [ 5 ]. These adverse effects of cisplatin-induced … WebJul 3, 2024 · Pirfenidone is an anti-fibrotic drug used in the treatment of idiopathic pulmonary fibrosis and has also anti-proliferative activities. Mesothelioma cell proliferation was decreased by pirfenidone alone or in combination with cisplatin. Pirfenidone also decreased significantly Transwell migration/invasion and 3D collagen invasion.

Did you know?

WebChemotherapy has dramatically improved the prognosis, and bleomycin, etoposide, and cisplatin (BEP) combination chemotherapy appears to be the most effective combination regimen. A 23-year-old woman was admitted to our hospital with worsening abdominal distention and a lower abdominal mass. WebThe administration of aerosol bronchodilators and corticosteroids are used by several patients with respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis, bronchiectasis, and lung infection [32,33,34]. Bronchodilators are known to dilate the airways that are narrowed due to the underlying ...

WebAlthough cisplatin (cisPt) is one of the most often used cytotoxic drugs in the treatment of cancer, its clinical application is associated with nephrotoxicity 掌桥科研一站式科研服务平台 WebSep 8, 2024 · Interstitial lung disease (ILD) is a disease with progressive deterioration of respiratory function ( 1 ). ILD is an independent risk factor for lung cancer (LC). Among patients diagnosed with lung cancer, 5.8–15.2% of patients have ILD ( 2, 3 ).

WebMar 20, 2024 · Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with an undefined etiology and poor prognosis. The prevalence of lung cancer is much higher in IPF patients than in the general population, and lung cancer significantly worsens the prognosis of IPF [ 1 ]. WebAbstract. Combination chemotherapy that included bleomycin and cisplatin was administered to 45 evaluable patients (30 with cervix carcinoma and 15 with germ cell …

WebMar 20, 2024 · Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with an undefined etiology and poor prognosis. The prevalence of lung cancer is much …

WebPulmonary fibrosis (PF) is part of a larger group of more than 200 interstitial lung diseases (also known as ILDs) that are characterized by inflammation and/or scarring in the lung. In ILDs, the injury and damage … how to speakers workWebMar 6, 2024 · Pulmonary fibrosis is a chronic, progressive disease, meaning it worsens over time. Learning more about the disease can help you and your family cope. Attending pulmonary rehabilitation can help you manage your symptoms and improve your daily functioning. Having pulmonary fibrosis can cause fear and stress. how to spear brace bannerlordWebApr 15, 2024 · Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease with unclear pathogenesis. IPF is considered as a risk factor for lung cancer. … rcvbuf is not enough to hold preloadWebOct 15, 2024 · Cisplatin forms intrastrand crosslinks in DNA, which disturbs DNA replication and causes DNA damage, eventually inducing necrosis or apoptosis. Cisplatin-based chemotherapy is widely used to... how to spear fish warframeWebBackground A strategy for preventing cisplatin nephrotoxicity due to enhanced oxidative stress and inflammatory response is highly desirable. Thioredoxin-1 (Trx), an endogenous redox-active protein, rcv_transactions subject areaWebOct 25, 2024 · The most serious complications of bleomycin are pneumonitis (bleomycin-induced pneumonitis–BIP) and pulmonary fibrosis, but other lung pathology includes … rcv_shipment_linesWebJan 23, 2024 · Interstitial lung disease is the most common syndrome; it may progress to end-stage pulmonary fibrosis. The clinical presentation is typically subacute, with … rcv software